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KMID : 0361020230660100692
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Korean Journal of Otolaryngology - Head and Neck Surgery
2023 Volume.66 No. 10 p.692 ~ p.696
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A Case of Anaplastic Lymphoma Kinase Negative Anaplastic Large Cell Lymphoma of Sphenoid Sinus
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Park Chan-Hyeon
Yeon Eung-Rok
Park Ha-Young
Park Seong-Kook
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Abstract
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Anaplastic large cell lymphoma (ALCL) is a rare subtype of peripheral T cell lymphoma,which is clinically, pathologically, and genetically heterogeneous. The disease is characterizedby large CD30 positive anaplastic cells that usually have horseshoe or kidney-shaped nucleiand infiltrate lymph nodes. Given the rarity of ALCL and its non-specific symptoms, it ischallenging to consider a differential diagnosis at first; however, meticulous tissue biopsy andimmunohistochemical staining can diagnose it. Recently, we encountered a patient who com-plained of facial pain, trismus and numb of lip for three months and was diagnosed with ana-plastic lymphoma kinase negative ALCL of the sphenoid sinus. Here we report this rare casewith review literature.
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KEYWORD
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Lymphoma, large-cell, anaplastic, Sphenoid sinus
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